Fused pyrrolo[2,3-c]carbazol-6-ones: novel immunostimulants that enhance human interferon-gamma activity

J Med Chem. 1997 Sep 12;40(19):2994-6. doi: 10.1021/jm9702037.
No abstract available

Publication types

  • Comparative Study

MeSH terms

  • Adjuvants, Immunologic / chemical synthesis*
  • Adjuvants, Immunologic / chemistry
  • Adjuvants, Immunologic / pharmacology*
  • Carbazoles / chemical synthesis*
  • Carbazoles / chemistry
  • Carbazoles / pharmacology*
  • Cell Line
  • Dimerization
  • Drug Synergism
  • Enzyme Inhibitors / chemistry
  • Enzyme Inhibitors / pharmacology
  • HLA-DR Antigens / biosynthesis*
  • Humans
  • Indicators and Reagents
  • Interferon-gamma / pharmacology*
  • Molecular Structure
  • Protein Kinase C / antagonists & inhibitors
  • Pyrroles / chemical synthesis
  • Pyrroles / chemistry
  • Pyrroles / pharmacology
  • Staurosporine / pharmacology
  • Structure-Activity Relationship

Substances

  • Adjuvants, Immunologic
  • Carbazoles
  • Enzyme Inhibitors
  • HLA-DR Antigens
  • Indicators and Reagents
  • Pyrroles
  • Interferon-gamma
  • Protein Kinase C
  • Staurosporine